Clinical expertise

Mr Mario Petrou has clinical expertise in the following:

Mitral and tricuspid valve surgery

  • mitral valve repair surgery – complex bi-leaflet repair including, artificial neochordae, resection and non-resectional techniques, annuloplasty ring insertion
  • mitral valve replacement – mechanical and bioprosthetic
  • tricuspid valve repair or replacement
  • re-do mitral and tricuspid valve surgery
  • AF ablation and left atrial appendage exclusion (concomitant to mitral valve surgery)

Aortic valve and aortic root surgery

  • aortic valve replacement – conventional and mini-incision
  • aortic valve cusp repair techniques
  • valve sparing aortic root replacement for Marfan Syndrome (Re-implantation and Remodeling techniques)
  • PEARS procedure for Marfan Syndrome
  • the Ross operation in young adults
  • aortic root enlargement
  • complex re-do aortic root surgery for endocarditis (including homograft insertion)
  • Ross-PEARS combined procedure

Major intra-thoracic aortic surgery

  • aortic root and ascending aortic aneurysm repair
  • replacement of the aortic arch (Elephant trunk procedure)
  • replacement of the proximal descending aorta

Coronary artery bypass grafting

  • on-pump and off-pump
  • total arterial grafting
  • re-do surgery
  • combined coronary and valve surgery

He was named clinical director for Cardiovascular services at Royal Brompton Hospital in December 2022 and is co-lead for cross-site cardiac surgery.


Mr Mario Petrou attended University College London attaining his MBBS in 1990, he then went on to achieve his PhD in 1996. He was a cardiothoracic trainee at the Royal Brompton Hospital from 1997 to 2002 before being appointed a Consultant Cardiac Surgeon in 2002.

After this, he moved to John Radcliffe Hospital in Oxford in 2011. He was head of programme for complex aortic surgery and clinical lead for cardiac surgery in Oxford before returning to the Royal Brompton Hospital in 2019.


Mr Mario Petrou has published over 80 peer-reviewed journal papers and other publications. He was awarded the McCormack Gold Medal for his outstanding performance in the Intercollegiate Examination in Cardiothoracic Surgery (Part III FRCS) in 2001