Clinical expertise

Dr Alison Duncan is the lead interventional echocardiologist for adult structural heart disease at The  Royal Brompton Hospital, and has imaged-guided >1500 TAVI procedures, >400 transcatheter mitral and >100 tricuspid edge-to-edge repairs, 55 transcatheter mitral valve implantations with the Tendyne device, a revolutionary technology for mitral-valve replacement (including the first-in-man Tendyne device implantation) and >40 transcatheter transventricular mitral neochordal procedures.

She is chairperson for the weekly aortic valve multidisciplinary team meeting and provides imaging support for twice weekly mitral and tricuspid valve multidisciplinary team meetings.

In addition, Dr Duncan is a member of:

  • the British Society of Echocardiography
  • the British Society of Heart Failure
  • the Heart Valve Society
  • the Acute Cardiovascular Care Association
  • the British Cardiovascular Society (as a faculty member)
  • London PCR Valve Therapies
  • Transcatheter Mitral Valve Interventions (UK and Ireland)
  • CSI Frankfurt
  • the International Society for Minimally Invasive Cardiothoracic Surgery

Dr Duncan is the UK chief investigator for the Global Tendyne Early Feasibility Study and is the principal investigator for both the Harpoon Tracer trial and Global Apollo trial (transcatheter Intrepid device). Additionally, she is the only UK imaging proctor for transcatheter mitral valve implantation (Tendyne) and repair (Neochord and Harpoon).



Biography

Dr Alison Duncan (MBBS BSc PhD FRCP FESC) is Associate Specialist in Cardiology and Transcatheter Valve Therapies at The Royal Brompton Hospital. She has more than 28 years’ experience in clinical transthoracic (TTE), transoesophageal (TOE), stress, and 3D echocardiography and has held full British and European Accreditation in both TTE and TOE since 2014.

She achieved her First Class PhD from Imperial College London in 2004 on “Physiological Stress Echo and Heart Failure”, was awarded Fellowship to the Royal College of Medicine London in 2019, was appointed Honorary Senior Lecturer at Kings College London in 2021, and became a Fellow of the European Society of Cardiology in 2024.

She has a postgraduate degree in Medical Education, and is the current Secretary of the British Heart Valve Society.


Research

Dr. Duncan is the UK Chief Investigator for the Global Tendyne Early Feasibility Study and image-guided the first world-wide Tendyne procedure in 2014. She is also the UK Chief Investigator for the international RESOLVE-MR, CHOICE-MI, and Mitral Valve (TENDER) registries, UK Chief Investigator for the multicentre transcatheter mitral valve repair procedure using the first iteration Edwards Harpoon device, and is Principal Investigator for the Apollo-EU trial (transcatheter transfemoral mitral valve implantation).

She is also the Principle Investigator for the International VDyne Vista-EU clinical trial assessing the VDyne transcatheter tricuspid valve replacement system, and is trainer for the International T-Heart transcatheter tricuspid valve replacement system.

Her research interests are physiology and transcatheter valve intervention.

Publications

Dr. Duncan has published over 100 original articles in peer-reviewed cardiology and cardiothoracic journals, has a Research Interest Score of 1492, 3130 Citations, and a H Index of 32.

Teaching

Dr. Duncan is a faculty member of, and teacher/ trainer for London PCR Valve Therapies, PCR Imaging Valves (Madrid), CSI Frankfurt, Heart Valve Society, BISMICS, EACTS, ISMICS, the British Cardiovascular Society, Transcatheter Mitral Valve Interventions (UK and Ireland), and the European PCR Tricuspid Focus Group. As such she has been an invited lecturer at over 120 national and international meetings.